From stresses imposed during mastication to facial expressions associated with speech production, the temporomandibular joint (TMJ) is one of the most load-bearing organs in the human body. It’s intricacies and unique curved shape pose challenges to recreate from bone grafts.

In a paper published in Science Translational Medicine this month, researchers at Columbia University managed to grow replacement jawbones, along with their joints….from the stem cells of pigs!

The researchers say they hope the same sort of technique may someday be used to grow other replacement bones and joints, including knees.

“It’s preliminary, but it is very exciting. I’m glad it is happening while I’m still practicing.”

- Dr. Sidney Eisig, Chair of Hospital Dentistry at Columbia University

For more about this study and clinical trials to follow, check out this New York Times feature article here.